The Human Brain and Spinal Fluid Resource Center (HBSFRC) was established in 1961. The Center is supported by NINDS / NIMH, the Department of Veterans Affairs, principally the National Multiple Sclerosis Society.

The mission of the HBSFRC is to provide high-quality samples of human tissues and fluids to scientific investigators, in hopes of supporting the discovery of treatments and cures for neurological diseases and disorders.